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140 documents found matching dt:article.
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1.  Konstam MA et al Cardiovascular thrombotic events in controlled, clinical trials of rofcoxib Circulation 2001 Nov; 104(19); 2280-8
Document Date: 20011101
Search Terms in Context: to Merck and Co and Pharmacia, and Dr Konstam also has been a paid consultant to Pfizer Inc. Neither has been compensated for work on this article. Drs Reicin, Shapiro, Sperling, Barr, and Gertz are employees of Merck Research Laboratories, Merck and Co, Inc. As such, they receive financial compensation that includes stock ownership and stock options. This article originally appeared Online on October
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2.  K. Green et al Pronounced Reduction of in vivo Prostacyclin Synthesis in Humans by Acetaminophen Prostaglandins, Mar. 1989, vol. 37:311-315
Document Date: 19890301
Author: Green, K
Search Terms in Context: * * * PROSTAGLANDINS *< ,?.*t • :w numeric» or ar vrvo BT JCRMUJHJW (YJÜUtCRHttZO Great»,, v. Drvota» and O. veetesqwiet ___** Clinical Chaaiatrr and Blood Coagulation Vaseline*» scapitai, B-104 01 Stockholm, ^^ BBISSaCf. ri + tba affact of a aiuola doaa of 500 «9 acetaminophen {pttracetanol) on the in vivo synthesis of prostacyclin va* studied In healthy volimtaara by neaaureaents of tba urinary axeratio» of 2,3-dinor-6~*eto-FOFlft, ¿cet- ¦ enlnophen fines* » ^»**»4 *~*-*-fi»n of proetacvSEfiT j inane eynthssla. Thus, acetaminophen nay at least theoretically be ólaadvantagsous for patianta auf faring from diaaaaaa vhara prostacyclin aadiatad vaacular dafanco aechanlsae ara activated, like nyooerdlal infarction, daap vain throaboaia and following surgery« wt Hon-ataroldal antl-lnflasMatory drugs (MtAIDs) bava antl-inxlamvstory, analgesic and antipyretic actions and «oat BSAIDe «loo affaot platelet function (1). However, la contrast to NSAID» acetaminophen, a vidaly osad anal
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3.  Economic evaluation of rofecoxib vs. non-selective . . .
Document Date: 20000504
Search Terms in Context: of osteoarthritis. Confidential - Subject To Protective Order MRK-ABWÛ016539 pgNbr=16 Pellissier et al. 17 ACKNOWLEDGMENTS The'authors thank Alan Morrison, Ph.D. for assisting in the preparation of this article. Confidential - Subject To Protective Order MRK-ABW0016540 pgNbr=17 Pellissier et
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4.  Comparison of upper gastrointestinal toxicity of Rofecoxib and Naproxen in patients with rheumatoid arthritis
Document Date: 20001123
Search Terms in Context: The New England Journal of Medicine COMPARISON OF UPPER GASTROINTESTINAL TOXICITY OF ROFECOXIB AND NAPROXEN IN PATIENTS WITH RHEUMATOID ARTHRITIS Claire Bombardier, M.D., Loren Laine, M.D., Ause Reicin, M.D., Deborah Shapiro, Dr.P.H., Ruben Burgos-Vargas, M.D., Barry Davis, M.D., Ph.D., Richard Day, M.D., Marcos Bosi Ferraz, M.D., Ph.D., Christopher J. Hawkey, M.D., Marc C. Hochberg, M.D., Tore K. Kvien, M.D., and Thomas J. Schnitzer, M.D., Ph.D., for the VIGOR Study Group Abstract Background Each year, clinical upper gastrointestinal events occur in 2 to 4 percent of patients who are taking nonselective nonsteroidal antiinflammatory drugs (NSAIDs). We assessed whether rofecoxib, a selective inhibitor of cyclooxygenase-2, would be associated with a lower incidence of clinically important upper gastrointestinal events than is the nonselective NSAID naproxen among patients with rheumatoid arthritis. Methods We randomly assigned 8076 patients who were at least 50 years of age (or at least 40 years of age
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5.  Catella-Lawson, et al: Effects of Specific Inhibition of Cyclooxygenase-2 on Sodium Balance, Hemodynamics and Vasoactive Eicosanoids
Document Date: 19990101
Author: Catella-Lawson
Search Terms in Context: 1 Reference 82 Catella-Lawson F, McAdam B, Morrison BW, et al. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids, J Pharmacol Exp Thcr 1999;289(2):735-41. MRK-00420019123 pgNbr=1 MK-0966, Reference 82 2 0G22-35S5O9/2892-0735$03.G0/0 The Journal of Phakmacglogy amd Experimental Therapeutics Copyright© 1999 by The American Society for Pharmacology and Expérimental Therapeutics JPET 289:735-741, 1999 Voi, 269, No. 2 Printed in U,S,A ^l»****«i«H*i*H*ata(ta^li***ta*«^*(i^^»t*"»*l ^*t*t***+***++*********+*t0È+*Ê^^++*Ê+È^^i**mm*#*mm*m*mmmmmmmmi*^*r*+mtr* nmiivnwHRPnnmHtnMiiiPvwtnMPnpwim Effects of Specific Inhibition of Cyclooxygenase-2 on Sodium Balance, Hemodynamics, and Vasoactive Eicosanoids1 FRANCESCA CATELLA-LAWSON,2 BRENDAN MCADAM,2'3 BRIGGS W. MORRISON, SHIV KAPOOR, DEAN KUJUBU, LISA ANTES, KENNETH C. LASSETER, HUI QUAN, BARRY J. GERTZ, and GARRET A. RTZGERALD The EUPenn Group of investigators at the Center for Experimental Therap
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6.  Risk of CV Events Associated with Cox-2 (Topol et.al.) WITH INDEX
Document Date: 20010822
Search Terms in Context: JAMA The Journal of the American Medical Association August 22/29, 2001 pgNbr=1 terment of the Public Hi JAMA The Journal ot the American Medical Association ¦jiuii»n>i:]ffS!iia ORIGINAL CONTRIBUTIONS G A Couiir/.. M J. Stampffr. C. S Fixhs Use of Nonprescription Weight Loss Products: Results From a Multistate Survey........................................................................930 H. M. BlaNCK. L K. Khan. M K. SCbduLa Cost-effectiveness of Vitamin Therapy to Lower Plasma Homocysteine Levels for the Prevention of Coronary Heart Disease: Effect of Grain Fortification and Beyond ..........................................................936 CARING FOR THE CRITICALLY ILL PATIENT Should Immunonutrition Become Routine in Critically III Patients? A Systematic Review of the Evidence............. d k heyunq. f. NOVAK,j. w. DlWVER. M.Jain, K.Su. U SuaiNEft Smoking Among Japanese Physicians SPECIAL COMMUNICATION Risk of Cardiovascular Events Associated With Selective COX-2 Inhibitors....
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7.  Patrono, Carlo et al Platelet-Active Drugs: the relationships among dose, effectiveness, and side effects: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest Supplement 2004; 126; 234-264
Document Date: 20040901
Author: Patrono, Carlo
Search Terms in Context: Platelet-Active Drugs: The Relationships Among Dose, Effectiveness, and Side Effects The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Barry CoBer, MD; MDiJaek Jfir*n> MD, FCCP- rmd Cario Patrono, Carnet A Gerald Both, MD lids article discusses platelet active drugs as part of the Seventh American College of Chest Physicians Conference on Antithrombotic
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8.  Low-dose Gabapentin in the treatment of painful diabetic neuropathy:A placebo-controlled, double-blind, crossover trial
Document Date: 00000000
Author: Gorson, Kenneth|Schott, Cecilia|Rand, William|Herman, Robert|Ropper, Allan
Corporate Author: St. Elizabeth's Medical Center|Tufts University School of Medicine
Search Terms in Context: 08-25-1997 07:57AM FRGM NEUROLOGY TO 912013165007 P.02 Low-Dose Gabapentin In The Treatment Of Painful Diabeti* Neuropathy: A Placebo-Controlled, Double-Blind, Crossover Trial Kenneth C. Gorson, M.D. Cecelia Schott, RPh. WmiainM.lUiMl.PhD. Robert Herman, B.S. Alian B. Ropper, BID. Neurology Service, St. Elizabeth's Medical Center. Tufts University School of Mediriiic, Boston, MA AdDMmsadgments: This study was financially supported by an unrestricted educational grant fiom Warner Lambert Co. (Parke-Davis Pharmaceuticals), Parke-Davis supplied gabapentin fior the purposes of this study. We would like to dunk Gregory Allan and Margot Geoflrey for their assistances data collection. keywords: neuropathy, pain» gabapentin, diabetes Send correspondence to: Kennern C. Gorson, M.D., Division of Neurology, St. Elizabeth's Medical Center, 736 Cambridge Street, Boston, MA 02135, Phone #: 617-789-2375; FAX #: 617-789-5177. ÏY.06827 WLC FRANKLIN 00001 pgNbr=1 08-25-199
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9.  New Clinical Markers Predictive of Cardiovascular Disease: The Role of Inflammatory Mediators, Charles E Rackley, MD
Document Date: 00000000
Page Count: 37
Search Terms in Context: , and fibrinogen. In addition, a large, case-control study7 among patients with premature coronary artery disease identified multiple genetic vanants of thrombospondm associated with familial premature myocardial infarction, suggesting an important new avenue of research into the etiology of coronary atherosclerosis. This article investigates the value of C-reactive protein and closely interrelated
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10.  The New Science of Estrogens, Ronald W. Maddox, PharmD
Document Date: 00000000
Page Count: 31
Search Terms in Context: The New Science of Estrogens Ronald W Maddox, Pharm D Professor and Dean Campbell University School of Pharmacy Goal: This article is designed to bring pharmacists up to date regarding the pharmacology and pharmacodynamics of estrogen. Objectives: After reading this article, pharmacists should be able to do the following: Describe the primary indications for estrogen therapy. Discuss
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